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Why it’s so hard to diagnose Zika

When a Zika epidemic was at its height in the Americas two years ago, diagnostics makers began working feverishly to create diagnostic tests for a virus that few in the U.S. had heard of. A lack of testing capacity has hampered efforts to track Zika in Angola, where a largely unreported cluster of microcephaly cases has been linked to the virus, and left mothers vulnerable to an illness that can cause severe birth defects in developing foetuses. WHY IS IT SO HARD TO TEST FOR ZIKA?

Zika in Africa - Rare birth defect on the rise in Angola

Born in a poor neighbourhood of Angola’s capital Luanda, the 10-month old boy has microcephaly, a birth defect marked by a small head and serious developmental problems. Cula is one of at least 72 babies born with microcephaly in Angola between February 2017 and May 2018, suspected victims of an emerging Zika outbreak.

The 2018 leadership spill in numbers

After days of chaos in Canberra, Scott Morrison has emerged as the new leader of the Liberal party and the new prime minister of Australia. It's been almost impossible to keep track of every twist and turn in this Shakespearean drama, to help you get your head around it, we've pulled together the numbers that matter in the 2018 leadership spill.

Brewers, Dodgers tied after 10 innings in NLCS Game 4

LOS ANGELES (AP) — The Milwaukee Brewers and Los Angeles Dodgers are tied 1-1 after 10 innings in Game 4 of the NL Championship Series.

Trump: Khashoggi case 'guilty until proven innocent' like Kavanaugh

Donald Trump has compared Saudi Arabia being accused of murdering journalist Jamal Khashoggi to Brett Kavanaugh being accused of sexual assault. "Here we go again with, you know, you're guilty until proven innocent. Mr Kavanaugh was sworn in as a US Supreme Court judge on 6 October after denying allegations that he assaulted Dr Christine Blasey Ford when they were at high school together.

Israeli jets strike Gaza after rocket lands in Beersheba - army

GAZA/JERUSALEM (Reuters) - Israeli jets struck targets in the Gaza Strip early on Wednesday after a rocket fired by Palestinian militants enclave struck a house in the southern Israeli city of Beersheba, the Israeli military said. A medical official told Israel Radio that three people were taken to hospital after the rocket struck the house. Residents in the Gaza Strip said jets had targeted eight locations.

Analysis: Trump's Saudi bet has become much riskier

WASHINGTON (AP) — President Donald Trump put a big and risky bet on Saudi Arabia and its 33-year-old crown prince. It's now become much riskier.

America's most famous pimp, poised for elected office, dies

PAHRUMP, Nev. (AP) — America's most famous pimp partied for days with porn stars, political pals and others to celebrate his 72nd birthday, but the revelry ended when Dennis Hof was found dead in one of his Nevada brothels.

French leftist leader reacts furiously to anti-corruption raids

Anti-corruption investigators on Tuesday raided the home and party headquarters of French hard-left leader Jean-Luc Mélenchon, who broadcast the raids live from his mobile phone. The raids, part of a long-running investigation into the alleged misuse of European Parliament funds to pay party employees, took place at the offices of La France Insoumise (France Unbowed) in central Paris and Mélenchon's private residence. "This is a politically motivated act, it's an act of political aggression," Mélenchon said in a dramatic live broadcast on his Facebook page as officers searched the premises.

Fleury ties for 10th on NHL wins list, Vegas tops Sabres 4-1

LAS VEGAS (AP) — Marc-Andre Fleury earned his 407th win to tie Glenn Hall for 10th place on the NHL list, and the Vegas Golden Knights beat the Buffalo Sabres 4-1 Tuesday night.

Resignation shakes up Alaska's governor's race

JUNEAU, Alaska (AP) — In a stunning October surprise, Alaska's lieutenant governor resigned Tuesday for making unspecified "inappropriate comments," imperiling the re-election hopes of Gov. Bill Walker, a man with whom he shared a brother-like bond.

Top Asian News 5:33 a.m. GMT

SRINAGAR, India (AP) — Anti-India protests and clashes erupted in the main city of disputed Kashmir on Wednesday shortly after a gunbattle between militants and government forces killed at least two suspected rebels and a counterinsurgency police official. The gunbattle began early Wednesday after troops cordoned off a neighborhood in Srinagar on a tip that some rebels were present in a civilian home, police said. The exchange of gunfire lasted for about half an hour, police said, leaving two militants and a police official dead. At least three soldiers were also injured in the fighting. No further information was immediately available.

Fighting in Kashmir's main city leaves 3 combatants dead

SRINAGAR, India (AP) — Anti-India protests and clashes erupted in the main city of disputed Kashmir on Wednesday shortly after a gunbattle between militants and government forces killed at least two suspected rebels and a counterinsurgency police official.

Democrats' not-so-secret plan to fight midterm malaise

WASHINGTON (AP) — They're asking pastors to text their congregants about the importance of voting. They're connecting with thousands of Puerto Ricans displaced by Hurricane Maria. And they're relying on groups like the NAACP, which has tripled its spending from 2016 to energize black voters.

Feinstein and rival de Leon, both Democrats, set to debate

SAN FRANCISCO (AP) — U.S. Sen. Dianne Feinstein and fellow Democrat Kevin de Leon are set to face off Wednesday in their only scheduled debate ahead of Election Day.

British royals reign over drought-stricken Australian town

Britain's Prince Harry and his wife, Meghan, arrived with the gift of much-needed rain and cheer on Wednesday for the rural Australian city of Dubbo, where farmers are struggling with a prolonged drought. The prince charmed the crowd at a picnic in the town's main park, standing at a podium in pouring rain with Meghan holding an umbrella over him, on the second day of their Pacific tour, which takes in Australia, New Zealand, Fiji and Tonga. "The rain is a gift!" Prince Harry told the thousands who had come out to see the royal couple in Dubbo, about 300 km (185 miles) northwest of Sydney.

The top 10 largest US Jackpots

Lottery players will have a chance at winning an estimated $868 million jackpot in Friday night's Mega Millions drawing, which would be the second-largest prize in U.S. history. Here is a look at the 10 largest U.S. jackpots that have been won and the states where the winning tickets were sold:

What is the Northern Ireland backstop?

The Ireland backstop serves as a safety net in the event of a no-deal Brexit, protecting an open border on the island of Ireland.

Mothers of babies afflicted by Zika fight poverty, despair

Nearly three years after a Zika outbreak in Brazil caused thousands of cases of microcephaly and other devastating birth defects in newborns, Reuters returned to check on the mothers and their children. In Angola, dozens of babies born with microcephaly since 2017 appear linked to the same strain of Zika that hit Latin America. In northeastern Brazil, we spoke with nearly 30 mothers who contracted the Zika virus during pregnancy.

Asia shares echo Wall Street cheer, China more muted

SYDNEY (Reuters) - Asian equities got some welcome relief on Wednesday after upbeat U.S. earnings reports drove a rebound on Wall Street and helped restore a little faith in emerging market stocks and currencies.

No winning Mega Millions ticket; jackpot climbs to $868M

DES MOINES, Iowa (AP) — No winning lottery ticket was sold for the latest Mega Millions drawing, meaning the jackpot climbs to $868 million.

Pompeo says Saudis committed to complete probe into journalist's disappearance

Saudi Arabia has committed to conducting a complete investigation into the disappearance of journalist Jamal Khashoggi, U.S. Secretary of State Mike Pompeo said on Wednesday before departing the kingdom for Turkey. Pompeo said he would meet with President Tayyip Erdogan in the Turkish capital Ankara, two weeks after Khashoggi vanished when he visited the Saudi consulate in Istanbul to collect documents he needed for his planned marriage. Earlier, President Donald Trump gave Saudi Arabia the benefit of the doubt in Khashoggi's disappearance, while U.S. lawmakers pointed the finger at the Saudi leadership and Western pressure mounted on Riyadh to provide answers.

Harry and Meghan get wet in drought-stricken Outback town

DUBBO, Australia (AP) — The Duke and Duchess of Sussex have been jokingly thanked for bringing England's notoriously inclement weather to a drought-stricken Outback town in a rain-drenched visit to Dubbo during their Australian royal tour.

AP FACT CHECK: Cruz, O'Rourke claims cite taxes, immigration

Democratic Rep. Beto O'Rourke abandoned his optimistic tone and attacked Republican U.S. Senator Ted Cruz as "Lyin" Ted in their second debate before the election, borrowing a nickname first used by President Donald Trump.

Flash Flooding Hits Fredericksburg, Texas, After Llano River Bursts Its Banks

Texas Governor Greg Abbott declared a state of disaster in 18 counties in central and south Texas on Tuesday, October 16, as severe flooding hit the state.The floods, brought on by heavy rainfall, forced the closure of several parks and lakes as authorities conducted search and rescue missions.This video shows flooding from the North US Highway 87 near Fredericksburg, travelling over the Llano River. Credit: Danielle Maloney via Storyful

Changing Orange County, California, gives Democrats hope

FULLERTON, Calif. (AP) — Pushy midday shoppers nose their carts through the Korean market, stocking up on bottled kimchi and seaweed spring rolls. A few doors away, customers grab pho to go at a Vietnamese takeout counter. Across the street, lunchtime diners line up for tacos "al pastor" — spit-roasted pork — at a Mexican-style taqueria.

Brewers, Dodgers tied after 9 innings in NLCS Game 4

LOS ANGELES (AP) — The Milwaukee Brewers and Los Angeles Dodgers are tied 1-1 after nine innings in Game 4 of the NL Championship Series.

The surprising loneliness of becoming a parent 

“I don’t know what I expected motherhood to be, but I never expected it to be lonely” 24-year-old single Mum Remi tells me as she sits on the floor playing with her baby daughter.  

Mega Millions jackpot now $868M, 2nd largest in US history

DES MOINES, Iowa (AP) — The already-giant Mega Millions prize is now at $868 million after a drawing Tuesday night turned up no winners.

Trump tells AP he won't accept blame if GOP loses House

Facing the prospect of bruising electoral defeat in congressional elections, President Donald Trump said Tuesday that he won't accept the blame if his party loses control of the House in November, arguing his campaigning and endorsements have helped Republican candidates. In a wide-ranging interview three weeks before Election Day, Trump told The Associated Press he senses voter enthusiasm rivaling 2016 and he expressed cautious optimism that his most loyal supporters will vote even when he is not on the ballot. "No, I think I'm helping people," Trump said.

Trump tells AP he won't accept blame if GOP loses House

Facing the prospect of bruising electoral defeat in congressional elections, President Donald Trump said Tuesday that he won't accept the blame if his party loses control of the House in November, arguing his campaigning and endorsements have helped Republican candidates. In a wide-ranging interview three weeks before Election Day, Trump told The Associated Press he senses voter enthusiasm rivaling 2016 and he expressed cautious optimism that his most loyal supporters will vote even when he is not on the ballot. "No, I think I'm helping people," Trump said.

Bono resigns as USA Gymnastics president after 4 days

When former California Congresswoman Mary Bono took over as the interim president for USA Gymnastics last week, she pointed to the opportunity to "reconnect" with a sport she loved growing up.

Trump criticizes rush to condemn Saudi Arabia over Khashoggi

President Donald Trump on Tuesday criticized rapidly mounting global condemnation of Saudi Arabia over the mystery of missing journalist Jamal Khashoggi, warning of a rush to judgment and echoing the Saudis' request for patience. In an interview with The Associated Press, Trump compared the case of Khashoggi, who Turkish officials have said was murdered in the Saudis' Istanbul consulate, to the allegations of sexual assault leveled against Supreme Court Justice Brett Kavanaugh during his confirmation hearing. "I think we have to find out what happened first," Trump said.

'Trump from Pahrump': Most famous US pimp found dead

A pimp whose brothel featured in a TV series and who fashioned himself as a Donald Trump-style political candidate has been found dead. Dennis Hof was found dead by porn star Ron Jeremy and a friend who went to wake him for a meeting on Tuesday, hours after his weekend-long 72nd birthday party, his campaign manager Chuck Muth said on Twitter. The strip club owner, who ran five legal brothels in Nevada, styled himself as America's best-known pimp after appearing on TV show Cathouse.

Rocket fired from Gaza hits home in south Israel; 4 treated

JERUSALEM (AP) — A rocket fired from Gaza struck a residential home in southern Israel early Wednesday and the Israeli military began attacking militant sites in Gaza in response as days of rising tensions appeared to be erupting into a new round of violence.

AP source: Indians complain to MLB about Astros filming

The Houston Astros may be defending more than their World Series title. The champions are under scrutiny after Cleveland filed a complaint to Major League Baseball about a man associated with Houston attempting to film in the Indians' dugout during Game 3 of the AL Division Series last week. During the Astros' series-clinching win on Oct. 8 at Progressive Field in Cleveland, a man with a cellphone standing by the photographer's pit was removed "several times" by security personnel, a person familiar with the situation told The Associated Press on Tuesday night.

One of the people believed to have been involved in Jamal Khashoggi's disappearance reportedly identified as frequent travel companion of Mohammed bin Salman

One of the people suspected of being involved in the disappearance of journalist Jamal Khashoggi has been identified as a frequent travel companion of Saudi Crown Prince Mohammed Bin Salman, according to sources cited by The New York Times on Tuesday.At least at nine of the 15 people identified by Turkish authorities are believed to have worked for the Saudi security services, military or other government ministries, The Times said. ...

Canada now world's largest legal marijuana marketplace

TORONTO (AP) — Ian Power was among the first to buy legal recreational marijuana in Canada but he has no plans to smoke it. He plans to frame it.

Pompeo heads to Turkey as probe into Khashoggi case heats up

ANKARA, Turkey (AP) — Police searching the Saudi Consulate found evidence that Saudi writer Jamal Khashoggi was killed there, a high-level Turkish official said, as America's top diplomat flew to the country on Wednesday to discuss the probe.

Shanghai airport automates check-in with facial recognition

It's now possible to check in automatically at Shanghai's Hongqiao airport using facial recognition technology, part of an ambitious rollout of facial recognition systems in China that has raised privacy concerns as Beijing pushes to become a global leader in the field. Shanghai Hongqiao International Airport unveiled self-service kiosks for flight and baggage check-in, security clearance and boarding powered by facial recognition technology, according to the Civil Aviation Administration of China. Similar efforts are underway at airports in Beijing and Nanyang city, in central China's Henan province.

Indian state won't ease crackdown on crime despite Apple manager's death

Private security guard Ajit Singh Rana says he supports a police crackdown on gangsters in India's most populous state, even after cops gunned down an Apple executive at a road stop in what human rights activists say was the latest in a series of extra-judicial killings. Police have said the shooting was an accident, but are adamant there will be no let-up in the anti-crime campaign, which is popular with many people in India's most politically important state. "Goons and criminals have held back the state for years," said Rana, 31, who guards a river-front park in Uttar Pradesh's capital Lucknow in the evening and is the supervisor of a group of street cleaners in the morning.

After storm shuts down radio stations, 2 hosts carry on

ORLANDO, Fla. (AP) — First Hurricane Michael damaged the radio station where they worked and then the owner shut the station down permanently — but that hasn't stopped two Florida radio hosts from continuing their mission of informing their listeners during the disaster.

AP Top Extended Financial Headlines at 12:19 a.m. EDT

Asian shares climb as strong US corporate earnings, data calm concern about softening growth